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Bio B2BMegaPro Biomedical Co., Ltd. 〉MPB1523: MRI Contrast agent

MPB1523: MRI Contrast agent

MPB1523: MRI Contrast agent

MPB1523 is a pegylated iron oxide nanoparticle. The compound holds high relaxivity for MRI image contrast and high macrophage uptake efficiency. After MPB1523 were uptaken by macrophage cells, the lymph nodes of metastatic tumors appeared very different in MRI signal changes from those of nonmetastatic tumors. The metastatic lymph nodes tended to be void of the labeling of contrast agent while the nonmetastatic ones were loaded with the contrast agent. The findings support the potential usage of MPB1523 when given intravenously for tracking serial lymph nodes in MRI lymphography for detecting metastasis.

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Overview
MPB1523: MRI Contrast agent
 
MRI lymphography is important to noninvasively determining whether a primary tumor has entered the stage of metastasis. The importance of MRI lymphography is to track the tumor cells in the serial lymph nodes thus to assist with surgical planning of complete removal.
 
MPB1523 is a pegylated iron oxide nanoparticle. The compound holds high relaxivity for MRI image contrast and high macrophage uptake efficiency. After MPB1523 were uptaken by macrophage cells, the lymph nodes of metastatic tumors appeared very different in MRI signal changes from those of nonmetastatic tumors. The metastatic lymph nodes tended to be void of the labeling of contrast agent while the nonmetastatic ones were loaded with the contrast agent. The findings support the potential usage of MPB1523 when given intravenously for tracking serial lymph nodes in MRI lymphography for detecting metastasis.  
 
Application
MRI lymphography is important to noninvasively determining whether a primary tumor has entered the stage of metastasis. The importance of MRI lymphography is to track the tumor cells in the serial lymph nodes thus to assist with surgical planning of complete removal.
 
Collaboration Options
product license out and clinical co-development
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