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Bio B2BACT Genomics 〉Comprehensive Genomic Profiling Service

Comprehensive Genomic Profiling Service

Comprehensive Genomic Profiling Service

Most powerful in immunotherapy prediction with accurate targeted, chemo, and hormonal therapy evaluation.
Comprehensive NGS panel design of 440 genes and provide medical report in 14 calendar days.

Request for Collaboration
Overview
ACTOnco®+ : Comprehensive Genomic Profiling Service is used to examine the genetic mutations in cancer patients for their personalized treatment plan. It is a breakthrough product to support current clinical guideline. Using next generaion sequencing (NGS) to test 440 cancer-related genes, ACTOnco®+ won Symbol of National Quality (SNQ) and National Innovative Award in Taiwan, Frost & Sullivan product strategy award in Singapore, and the winner of "2019 Taipei Biotechnology Award" . 
 
Features
  •  Most powerful in immune checkpoint inhibitor biomarker, Tumor Mutational Burden(TMB), calculation
  •  Comprehensive NGS panel designof 440 genes includes genes related to pharmacogenomics beside immunotherapy, targeted   therapy, chemotherapy and hormonal therapy.
  •  AI-powered bioinformatics analysis of cancer genetic mutations of SNV & Indel, CNV, MSI and TMB in cancer signaling pathways.
  •  High-quality test result in CAP-certified lab
  •  Fast turnaround time with 14 calendar days  
Specifications
  • Comprehensive Exon Sequencing : 440 Cancer-related genes
  • Hotspots: > 6800
  • NGS Sequencing Mean Depth:> 800 X
  • Sample Types : FFPE (5-20 unstained sections : 10µm/slide and 1H&E stained slide : 5µm)                                                                   *Cell block from pleural effusion, ascites or pericardial hydrops (≥1X106cells)
  • Prediction of Immunotherapy Response : Tumor Mutational Burden (TMB) & Microsatellite instability (MSI) testing
  • Addutional Test for ACTFusion™: Comprehensive testing of 31 fusion genes and 182 fusion transcripts
Application
All solid tumor patients including common cancer types such as breast, lung, colorectal cancer and rare cancer type.
Especially powerful to find effective drug options in the following situations:
  •  Newly diagnosed with complex cancer type
  •  Recurrent and metastatic cases
  •  Patient searching for treatment (and trials) options
  •  Diagnosed with advanced cancer or late-stage cancer
Collaboration Options
  • Clinical Services : Provide cancer genomic profiling to enable personalized treatment plan.
  • Biomarker Discovery : We provide comprehensive cancer genomic profiling to facilitate biomarker discovery. Customized assay is available.
  • Patient Stratification : From next generation sequencing, IHC and PCR assay, we utilize various platforms to screen patients prospectively.
  • Consultation : Our team of industry veterans and in-house clinical database offer insights to ensure smooth clinical trial operations.
  • CDx Development : We offer companion diagnostic development on NGS-based or CHIP-based multiplex qPCR platforms.
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